Iran’s Islamic Revolutionary Guard Corps (IRGC) says it struck several facilities in its retaliation against the US and Israel. 

The IRGC said in the first phase of retaliation, named “Truthful Promise 4,” Iran’s military struck the command of the US 5th Fleet in Bahrain as well as US bases in Qatar and the United Arab Emirates, and military targets in Israel.

They added Iranian attacks with missiles and drones are continuing and more information will be released later.

AP

Iran said Israeli-US airstrikes killed five students at a girls' school, the first confirmed fatalities in Iran in the operation.

The state-run IRNA news agency reported the strike happened in Minab in southern Iran.

Iran's paramilitary Revolutionary Guard has a base in the city.

Neither the US nor Israel has offered any details on the campaign so far.

Reporting with AP

London Gatwick Airport says some flights to and from the airport may experience delays or cancellations due to airspace restrictions in the Middle East. 

"Due to the ongoing situation in the Middle East, airspace restrictions have been introduced in parts of the region," a spokesperson said in a statement.

"This is a fast-moving situation, and we are expecting disruption to our Qatar and Emirates flights," the spokesperson said, adding that none had been cancelled at the moment.

The president of the European Commission, Ursula von der Leyen, says the developments in Iran are "greatly concerning". 

She said the European Commission would take "all necessary steps" to support European citizens in the region. 

"We call on all parties to exercise maximum restraint, to protect civilians, and to fully respect international law," she said. 

We are hearing that several explosions have been heard in Abu Dhabi, near the city's main airport, Reuters witnesses say.

In a show of support for Iran, the Iranian-backed Houthis in Yemen have decided to resume missile and drone attacks on shipping routes and on Israel . 

That's according to two senior Houthi officials, who spoke on condition of anonymity because there is no official announcement from the Houthi leadership.

One of the officials said the rebels’ first attack could come as soon as tonight.

The rebels ceased their attacks on the Red Sea shipping route as part of a deal with the Trump administration that also halted US strikes against the Houthis. 

They also stopped their attacks against Israel after an October ceasefire that halted major fighting in Gaza.

AP

Earlier this week there were hopes of a de-escalation as officials from the US and Iran met in Geneva for talks mediated by Oman.

After hours of negotiation there was no sign of a breakthrough to avert possible US strikes, but on Thursday the two sides said they would meet again soon.

They had planned to resume negotiations after consultations in their countries' capitals, with technical-level discussions scheduled to take place next week in Vienna, Omani Foreign Minister Sayyid Badr Albusaidi said in a social media post.

On Friday Albusaidi told CBS that a "peace deal is within our reach … if we just allow diplomacy the space it needs to get there."

Ukraine's foreign ministry blamed Iranian authorities for the escalation in Iran, adding that Kyiv stood with the Iranian people and repeating calls for a change of government there.

"The cause of the current events is precisely the violence and impunity of the Iranian regime, in particular the killings and repression of peaceful protesters, which have become particularly widespread in recent months," the foreign ministry said in a statement.

Reporting with Reuters

We are learning more about the first wave of the attacks on Iran. 

Israel and the US targeted Iran's Supreme Leader Ali Khamenei and Iranian President Masoud Pezeshkian with their attacks, according to an Israeli military official who has spoken to Reuters. The official said the results were not immediately clear.

In another report on the Reuters news agency, a Western official said the first wave of attacks targeted Iranian "military and political targets".

And we now have video looking out over Tehran that shows smoke rising over Supreme Leader Ali Khamenei's compound, Beit Rahbari. Khamenei had reportedly been sheltering. 

In the video, the women who are on the rooftop sound as if they're laughing in celebration. The ABC has heard other reports of Iranians celebrating and we are working to confirm them. Watch (and listen) to the video below. 

Donald Trump is expected to address his nation again on Saturday morning, local time, AXIOS says. 

It is unclear exactly what time we can expect the US president to speak. It is currently about 5am in Washington.